OAS2 antibody, Internal - 50 µg

Alternate_Names : 2'-5'-oligoadenylate synthetase 2 Applications : WB Species_reactivity : Hu Storage_Buffer : PBS, 2% Sucrose, 0.09% Sodium azide. Concentration : 0.5-1 mg/ml or th Form : 2'-5'-oligoadenylate synthetase 2 References : This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on ch romosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]